Mayo finds connection between anxiety, estrogen and Parkinson’s disease
by Erin Galbally, Minnesota Public Radio
April 13, 2005
Mayo neurologist James Bower led the study linking Parkinson’s and anxiety. He also worked closely on the study that revealed a connection between the disorder and ovary removal. Bower says in both cases the findings will be useful for scientists who continue to try to crack the disease. (Photo courtesy of the Mayo Clinic)
The Mayo Clinic released two studies Wednesday that begin to identify possible causes of Parkinson’s disease. In one, researchers found elevated anxiety levels increased the likelihood of developing the disease. In the second, researchers found women who have both ovaries removed also face an increased risk of developing the neurological problem. The findings were presented in Miami at the American Academy of Neurology.
Rochester, Minn. — Parkinson’s disease is a relatively rare disorder. It attacks neurons in the brain controlling muscle movement. Those who suffer from Parkinson’s have trouble walking and often constantly shake. For the past 10 years, Mayo neurologist James Bower has been studying the disease. Bower says he’s been looking for links between certain personality types and Parkinson’s.
“There have been studies in the past that have suggested that a less adventurous, less novelty seeking personality as well as certain psychiatric conditions especially anxiety and depression, that both of these might be linked to the later development of Parkinson’s disease,” Bower explains.
Mayo researchers led by Bower looked deeper for a possible link. They tracked down a group of about 4,000 who took a popular personality test back in the 1960s. Researchers then determined that just over a hundred developed Parkinson’s. Among those who did, a majority had received high scores for anxiety and pessimism. After crunching the numbers, Bower says it became apparent that those suffering from extreme anxiety might have as much as a 60-percent greater chance of developing the disease.
“We did find this association but now we need to figure out what it means,” says Bower. “One explanation is that anxiety is actually a cause for Parkinson’s disease. But there’s also an alternative explanation and that it’s not anxiety actually causing the illness but that maybe there’s another risk factor like a gene that leads to both anxiety and Parkinson’s later on. So we have to differentiate the two.”
Bower stresses that extreme anxiety is much more intense than normal worrying. And he says more research needs to be conducted to determine if anti-anxiety medication could make a difference when it comes to the likelihood of developing Parkinson’s.
In another study researchers determined that women who have both ovaries removed double their chances of developing Parkinson’s. The loss of natural estrogen seems to be responsible. Bower says there’s a similar link between the hormone and osteoporosis.
“What this study does is it tells us that not does natural estrogen seem to help the bones it also seems to help the brain in terms of Parkinson’s disease,” says Bower.
He says in many instances women have their ovaries removed as the result of some sort of medical emergency. But Bower says in cases where removal can safely be avoided it might a wise alternative to consider.
“They’re getting a hysterectomy for some other reason and the discussion with the surgeon is while I’m doing your hysterectomy and taking out your uterus, should I also take out your ovaries? And then if you don’t have ovarian cancer, it would be a less significant indication and that where there’s more of a play of discussing the risk benefit ratio,” he explains.
Bower expects research will continue. He says the findings should be especially useful to other scientists who share a determination to untangle Parkinson’s many remaining mysteries.
Mucuna pruriens in Parkinson’s disease: a double blind clinical and pharmacological study.
Katzenschlager R, Evans A, Manson A, Patsalos PN, Ratnaraj N, Watt H, Timmermann L, Van der Giessen R, Lees AJ.
Source
National Hospital for Neurology and Neurosurgery, London, UK.
Abstract
BACKGROUND:
The seed powder of the leguminous plant, Mucuna pruriens has long been used in traditional Ayurvedic Indian medicine for diseases including parkinsonism. We have assessed the clinical effects and levodopa (L-dopa) pharmacokinetics following two different doses of mucuna preparation and compared them with standard L-dopa/carbidopa (LD/CD).
METHODS:
Eight Parkinson’s disease patients with a short duration L-dopa response and on period dyskinesias completed a randomised, controlled, double blind crossover trial. Patients were challenged with single doses of 200/50 mg LD/CD, and 15 and 30 g of mucuna preparation in randomised order at weekly intervals. L-dopa pharmacokinetics were determined, and Unified Parkinson’s Disease Rating Scale and tapping speed were obtained at baseline and repeatedly during the 4 h following drug ingestion. Dyskinesias were assessed using modified AIMS and Goetz scales.
RESULTS:
Compared with standard LD/CD, the 30 g mucuna preparation led to a considerably faster onset of effect (34.6 v 68.5 min; p = 0.021), reflected in shorter latencies to peak L-dopa plasma concentrations. Mean on time was 21.9% (37 min) longer with 30 g mucuna than with LD/CD (p = 0.021); peak L-dopa plasma concentrations were 110% higher and the area under the plasma concentration v time curve (area under curve) was 165.3% larger (p = 0.012). No significant differences in dyskinesias or tolerability occurred.
CONCLUSIONS:
The rapid onset of action and longer on time without concomitant increase in dyskinesias on mucuna seed powder formulation suggest that this natural source of L-dopa might possess advantages over conventional L-dopa preparations in the long term management of PD. Assessment of long term efficacy and tolerability in a randomised, controlled study is warranted.
Elevating Dopamine is as important as working with the stress to the brain that makes Dopamine levels low to begin with. Glutathione normally keeps inflammation and oxidation down which reduces stress to your brain. In addition to improving Dopamine you should consider Glutathione supplementation.
Vitamin B12 Benefits
Disease and Your Health…
What is the Connection?
Would you like to really understand how vitamin B12 benefits your body? Instead of the usual laundry list of assorted benefits listed without explanation typical of many websites, this information will educate and make sense to you. Information is power… empower yourself now with the knowledge you need to achieve your best natural health.
Ready for the journey? Great. Lets go!
Vitamin B12 is fundamental to protein metabolism and DNA biosynthesis… major metabolic pathways dramatically affecting your health.
Consequently, vitamin B12 benefits are far-reaching… ranging from the formation of healthy red blood cells, generation of energy, control of mood, focus and concentration, protection from degenerative nerve damage that may lead to dementia and Alzheimer’s – even potential protection from athersclerosis and cancer
First, lets highlight vitamin B12 benefits and then we will take a closer look at how vitamin B12 works in your body. As a result, you will take away a high level of knowledge that you can actually apply to improve your health! Its all under your control.
Vitamin B12 Benefits You Can Experience
1) Vitamin B12 Regenerates Another Important B Vitamin Called,“Folic Acid” Without B12, Folic Acid Becomes Trapped in Your Body in a Metabolically Useless Form.
2) Vitamin B12 and Folic Acid Support Synthesis and Metabolism of Proteins and DNA Biosynthesis.Vitamin B12 Interveigns into These Essential Life Processes at Several Key Steps. For Example…
3) Healthy Red Blood Cells Depend on Vitamin B12 Driven Synthesis of DNA. Without B12, DNA Synthesis Shuts Down, Causing Megaloblastic Anemia. Symptoms Include Fatigue, Lack of Energy, Diarrhea, Nausea, Decreased Appetite, Weak Muscles, Headaches, Tingling Sensations and Sore Tongue.
4) Vitamin B12 Supports Synthesis of the Amino Acid “Methionine”Methionine is a Crucial Building Block of Proteins
5) Vitamin B12 Supports Synthesis of Another Amino Acid Called“SAM-e” SAM-e is Required for Over 100 Enzymatic Reactions Required for Normal Metabolic Activity Within Your Body
6) Vitamin B12 Promotes Activity of Hormones and Neurotransmitters Affecting Your Mood These Include Dopamine, Serotonin and Melatonin
7) Vitamin B12 Helps Reduce Dangerous Levels of“Homocysteine”Homocysteine is Toxic Amino Acid (Protein) Associated with Significant Cardiovascular Risk
8) Vitamin B12 Benefits Help Prevent Irreversible Neurological Impairment Peripheral and Central Nervous System Deterioration due to vitamin B12 deficiency has been Linked to Onset of Alzheimer’s Disease and Dementia
These vitamin B12 benefits are real and tangible. How can a single vitamin produce such a diverse array of benefits ranging from cardiovascular protection to cancer prevention?
Simple! Vitamin B12 benefits are linked by a common pathway in the chemistry of life… a metabolic pathway known as the “carbon shuttle”
My dad’s favorite food is fish. On his nights to cook, he whips up his usual salmon dinner. As a kid, I didn’t like salmon but my dad insisted fish was brain food and would make me smarter. Naturally, I didn’t believe him but I ate my dinner in case the fish might help me on my next test. Now, I’ve decided to research my dad’s theory and it so happens that he was right. The oil in fish contains omega-3 fatty acids, abbreviated as n-3 fatty acids, have numerous health benefits; some of which include cardiovascular disease prevention. The n-3 fatty acids reduce high blood pressure, increase lipoprotein or “good cholesterol” amounts, and lower the risk of heart disease (4). However, my dad was referring to neurological properties; therefore, I will focus on the positive effects of omega-3 fatty acids in mood disorders and memory.
As a preliminary note, n-3 fatty acids are polyunsaturated fatty acids or PUFAs. PUFAs are considered to be the building blocks of many neurotransmitters. Eicosaphentaenoic acid, EPA, and docosahexainoic acid, DHA, are two particular types of PUFAs that generate a healthy nervous system. EPA aids mostly in cardiovascular problems while DHA aids in neurological problems. Studies find DHA as a more effective contributor to memory and cognition since the fatty acids better maintain and generate neuron tissue. As a result, DHA is the primary n-3 fatty acid found in salmon, lake trout, herring, sardine, and tuna (1).
Most studies of EPA and DHA examine neurological development usually in infants and children. DHA added to infant milk formulas lead to optimal brain functioning in both premature and full term babies. In the womb, human fetuses subjected to high dosages of ethanol, due to the mother consuming too much alcohol, risk insufficient neurological development. The ethanol and other organic solvents exhaust DHA supplies in the fetus’s brain. Low levels of DHA in a child factor into the biological causes of mild neurological and behavioral problems (2). Deficiencies of DHA are hypothesized to possibly contribute to childhood ADHD, attention deficit hyperactivity disorder. Conflicting evidence forces this hypothesis to continue with further research (2, 3). On the other hand, accepted repercussions of low n-3 fatty acids levels in children are aggression, depression, and other behavior problems (2).
Low omega-3 fatty acid diets diminish dopamine levels, a monoaminegeric neurotransmitter. In 2000, a study by Zimmer et al. observed rats fed an n-3 fatty acid poor diet had a 90% reduction of dopamine released in their brains and mild damage to the dopaminergic synaptic vesicles (2). The neurotransmitter was unable to trigger communication signals to the next neuron. Similarly in a 1998 article in the Journal of Nutrition by Chalon, S. et al., rats fed a fish oil diet had a great grain capacity than those fed a control diet. The rats consuming higher quantities of fish oil had 40% greater dopamine levels in the frontal lobes (2). Scarce dopamine levels in human brain frontal lobes induce neurocognitive functions such as memory, problem solving, and attention are negatively affected (1). Furthermore, if low dopamine levels in humans affect attention, then perhaps this deficiency may be a contributing factor to ADHD. A more examined problem is the susceptibility to depression with low n-3 fatty acid diets and low dopamine amounts. Many animal studies have concluded low dopamine levels, as a result of depleted n-3 fatty acid diets, lead to behavioral problems.
Omega-3 fatty acids not only affect not only dopamine, but also serotonin. Neural membrane tissues contain DHA which facilitate signaling pathways (5). The DHA concentration in neuron membranes has a direct correlation to serotonin levels according to a 1995 study by Hibbeln and Salem. DHA reduction negatively affects either serotonergic receptors or serotonin-reuptake systems (5). Later Olsson et al. concluded a study suggesting a diet low in n-3 fatty acids reduces the amount of serotonin (2). Chronic dietary deficiencies in n-3 fatty acids have also found a 40-75% decrease in dopamine levels (2, DeLion et al). Furthermore, if there are scare amounts of serotonin, then signal relaying is hindered. Only high amounts of serotonin, resulting from a DHA rich diet, tend to facilitate neurotransmission.
A study by Norman Salem, Jr et al focused on the importance of DHA during rat neurological growth and development. The rats were placed in a Morris Water Maze which had four maze quadrants surrounded and separated by water. The rats ran through the mazes and had to reach at a designated platform. A group of rats were fed a DHA rich diet, while a second ground was fed a non-DHA diet. Escape latency, total number of seconds to reach the platform, and memory retention were timed. N-3 fatty acid fed rats demonstrated a faster escape latency and longer memory retention. These rats had a higher memory because of a 7% hippocampus brain level. Scientists noted, however, there was no density or totally number of neuron change (3). There must have been improved patterns of activity in the rat brain.
Numerous brain and behavior studies have provided insight to the beneficial aspects of DHA. Overall, omega-3 fatty acid rich diets seem to improve animal behavior. Since high levels of DHA in fish oil positively affect mammalian animal, perhaps this research may be applied to human behavior. I semi-support my dad’s claim that fish is brain food to make you smarter. I, however, would like to further expand that brain food, such as fish, feeds our mood and biological behaviors.
Involved in so many processes in the body from liver, ophthalmic, brain and lung functioning, Glutathione has been shown to be a very beneficial, functional medicine therapy. GlutaGenic makes the only high potency and absobabe Glutathione.
Benefits:
It is the major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms.
Regulation of the nitric oxide cycle, which is critical for life but can be problematic if unregulated
Through direct conjugation, it detoxifies many xenobiotics (foreign compounds) and carcinogens, both organic and inorganic. This includes heavy metals such as mercury, lead, and arsenic.
It is essential for the immune system to exert its full potential, e.g., modulating antigen presentation to lymphocytes, thereby influencing cytokine production and type of response (cellular or humoral) that develops, enhancing proliferation of lymphocytes, thereby increasing magnitude of response, enhancing killing activity of cytotoxic T cells and NK cells, and regulating apoptosis, thereby maintaining control of the immune response.
It plays a fundamental role in numerous metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation. Thus, every system in the body can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system and the lungs
Uses:
Glutathione by Inhalation for COPD
Glutathione is made in the body and used in every cell, but it is of special importance in lung tissue. It is helpful in emphysema, some asthma and even lung cancer. It can be inhaled as a spray in order to get a higher level directly to the needed lung area.
A simple home nebulizer allows treatment twice daily for only five to ten minutes and increases the removal of sticky secretions and gives greatly increased lung efficiency. One uses a solution of glutathione in a nebulizer and attaches that to the electric pump. Breathe in as much as you can during the five to ten minute treatment. If you need to stop during the treatment, simply shut off the pump and resume when ready.
Ophthalmic Drops (Stock #: 15269)
Glutathione/Vitamin C/DMSO 15ML 1.25/1.25/6.25%
Glutathione for injection: Glutathione injection is primarily for IVís for many different oxidative brain disorders, such as: Parkinsonís, MS and Alzheimerís. According to Dr. Perlmutterís research, frequent high dose IVís are very beneficial for ìFire in the Brain.î Watch out for his new book.
One of the most powerful antioxidants in the body
From: DrWhitaker.com
As I wrote about in the September 2003 issue of Health & Healing, chronic obstructive pulmonary disease (COPD) is a collective term for several diseases of the lungs. COPD most often refers to emphysema, which is almost always caused by smoking. Other ailments falling under the COPD category include chronic obstructive bronchitis and asthmatic bronchitis, which narrow the airways and fill them with mucus.
Conventional medicine holds that there is no remedy for COPD. Yet at the Whitaker Wellness Institute, we recently began utilizing a safe new therapy that has shown great promise: inhaled glutathione. Glutathione is the most efficient free radical scavenger in the airways, and dozens of studies have confirmed that free radical damage is a primary player in COPD. Although not particularly well absorbed when taken orally, the effects of inhaled glutathione are remarkable. (I have attached a medical journal article on this therapy, which includes a list of references.)
This treatment requires a doctor’s prescription. If you or someone you love suffers from chronic lung disease and would like to seek treatment at the Whitaker Wellness Institute, call (800) 488-1500. Or pass along this information and ask your doctor to help you implement these recommendations – and send me a note to tell me how it worked for you.
Protocol for Inhaled Glutathione
Glutathione 300 mg nebulized twice a day (Physicians note: vial = 200 mg/cc, draw 1.5 cc and place in nebulizer)
Treatments take five to ten minutes and may be continued as long as the patient remains symptomatic.
A nebulizer, sometimes called a breathing machine, transforms liquid medications into mists that can be inhaled. To get a nebulizer for home use you will need a prescription from your doctor. Nebulizers cost from $50 to more than $300 and are often covered by insurance. Below is one company that sells nebuliziers. Ask your physician for a referral to other medical equipment companies and for instructions in its use.
Vitamin C, multiple doses throughout the day, to bowel tolerance (minimum 10 grams per day)
Magnesium, 500 mg twice a day
Fish oil, 2 grams three times a day (6 capsules daily)
Beta-carotene, 300 mg per day (500,000 IU)
Vitamin A, 20,000 IU per day
N-acetyl-cysteine, 500 mg three times a day
Lycopene, 15 mg twice a day
IV vitamin C
Chronic obstructive pulmonary disease (COPD), a designation which includes emphysema, is a leading cause of death in America. This case study reports on the successful treatment of both acute and chronic emphysema with a novel agent. Much of the tissue damage in emphysema is thought to be mediated by an oxidative down-regulation of the activity of -1-proteinase inhibitor.1 This down-regulation has been shown in vitro to be slowed by glutathione, a sulfhydryl-containing tripeptide known to be a major antioxidant in the lung.2
Glutathione concentrations in bronchoalveolar fluid have been found to be inversely correlated with the degree of inflammatory activity in the lungs of smokers.3 Thiol compounds (i.e., compounds containing an -SH group) like glutathione have a history of use as mucolytics as well.4 Previous clinical trials of nebulized reduced glutathione have demonstrated the bioavailability and safety of up to 600 mg twice daily.5,6 The absorption of oral glutathione remains controversial, with animal studies suggesting significant absorption and some human studies showing little to none.7,8 Based on these findings, it appears inhalation might be the preferred route of administration for respiratory and perhaps systemic effect. We report the case of a man with an acute respiratory crisis due to emphysema and apparent bronchial infection that responded favorably to treatment with nebulized glutathione.
Abstract
We present the case of a 95-year-old man with an acute respiratory crisis secondary to emphysema and apparent bronchial infection. Treatment with nebulized glutathione led to a rapid resolution of the crisis, as well as a marked improvement in the chronic course of the disease. This treatment has been used since for a number of patients with emphysema. The safety and bioavailability of this method of delivery have been established in human studies. Preliminary results suggest efficacy for nebulized administration of glutathione in this patient population. We suggest this treatment can be considered an option for acute respiratory crises due to COPD.
Case Report
In 1997, a 95-year-old male with emphysema presented in a wheelchair and using an oxygen tank and mask necessitated by his acute illness. He was alert, responsive, and reported a productive cough with colorless sputum. His breathing was obviously labored.
He refused hospitalization and antibiotic treatment.
We chose to try a single trial dose of 2 ml of GlutaGenesis solution (prepared by GlutaGenic.com) nebulized and inhaled over a 5-10 minute period.) Due to the obvious immediate benefit, it was decided to continue this treatment with twice-daily administration and close monitoring by his family of his overall condition. He returned to the office in three days without wheelchair or oxygen tank. He showed no signs of respiratory distress, and no adventitious lung sounds were noted on auscultation. The patient reported his breathing was better than it had been in years. He continued daily treatment with glutathione until his death from congestive heart failure over two years later.
Conclusion
While resolution of the acute episode due to a mucolytic effect was the desired outcome of the glutathione treatment, the lasting improvement in breathing was unexpected.
Since we have no serial spirometry data available on this patient, placebo effect cannot be ruled out as an explanation for his marked response.
However, given the progressive nature of his disease, the dramatic and rapid change in physical findings, and the emphatic insistence of the patient for continued treatment, we believe placebo response to be an unlikely explanation. We have subsequently prescribed this preparation for six patients with emphysema, five of whom reported improved breathing after a single in-office application and who later requested to continue treatment. We also have found nebulized glutathione is best administered daily from 4 ml vials. We have also seen improved respiratory function associated with nebulized glutathione treatment in cases of chronic bronchitis and asthma.9 In the case of asthma patients we feel it is advisable to check urinary sulfite excretion to verify proper metabolism of sulfur compounds, as certain individuals appear to experience exacerbation of respiratory symptoms from exogenous sulfur compounds.10 In three cases of non-small cell lung cancer with effusion, the effusion resolved completely. Given the safety and promise of this treatment, combined with the paucity of other effective treatments for emphysema, we suggest this treatment be considered for widespread use.
Oral administration of glutathione doesn’t work as the digestive system breaks glutathione down into its amino acid building blocks. The GlutaGenic Glutathione suppository and nebulization overcomes these problems.
Every day we are exposed to hundreds of toxic chemicals such as solvents, petrochemicals, toxic metals, pesticides and more. Glutathione is the body’s main detoxifier and is singularly responsible for dealing with these poisons. Glutathione is considered to be the most powerful, most versatile, and most important of the body’s self-generated antioxidants.
Oral administration of glutathione doesn’t work as the digestive system breaks glutathione down into its amino acid building blocks. GlutaGenic suppository glutathione overcomes this problem. What makes this product truly revolutionary is that clinical case studies have demonstrated we are now able to raise tissue levels of glutathione by our ability to combine pure pharmaceutical grade Glutathione into our proprietary patent pending suppository base.
Organic coffee can be added (SEE THIS REPORT ON GLUTAJAVA) added to stimulate the production of glutathione-s-transferase, the enzyme that is required to attach these toxins to the glutathione molecule.
GlutaGenic Glutathione help to Detoxify Many Harmful Substances!
Pesticides and Herbicides
Approximately 1 billion pounds of pesticides, herbicides and fungicides are applied each year in the United States, with the usage doubling every 10 years. Less than 1% of these toxins applied ever find their way to the target pest. The rest goes into our food, water, air and soil. While organic food is better, it still has up to 50% the pesticide residue found on commercial food. Pesticides are carcinogens, mutagens, and neurotoxins and can damage the immune system and the endocrine system. Glutathione can help detoxify pesticides.
Car Exhaust and Cigarette Smoke
There are nearly 600 million vehicles on the world’s roads poisoning our atmosphere. In some cities like Los Angeles and Mexico City, daily smog reports are given in the newspapers and radio stations letting people know how safe it is to go outside and breathe the air. Comparing photographs of the atmosphere over the last 20 years, meteorologists have been able to document a significant toxic darkening of our skies. A thick cloud of poisonous air has settled over the planet, and while it is worse in some areas than others, the atmospheric changes are evident from pole to pole. Add to this the fact that some of us breathe smoke directly into our lungs with cigarettes, and the problem is only compounded. Glutathione detoxifies these poisons.
Alcohol
While moderate alcohol consumption has some benefits, alcohol also has a dark side. In the process of metabolizing alcohol, the liver turns it into formaldehyde. This is the same toxic fluid that is used in high school biology classes to preserve frogs and fetal pigs for dissection and what is currently used to embalm people. Formaldehyde is extremely toxic to the body and the faster you detoxify it, the better. Glutathione detoxifies alcohol and formaldehyde.
Bacterial and Fungal Toxins
Chronic bacterial and fungal infections in our intestines release their poisonous metabolic end products directly into our bloodstream. These toxins are carcinogenic and can also cause mood and memory disorders. Further exposure to mold toxins in our food supply and breathing air from mold infested buildings makes for additional exposure. Glutathione detoxifies these poisons.
Pharmaceuticals
Open any magazine and look at an ad for any pharmaceutical product. There on the back of the page is another page filled with fine print listing its side effects. Considering that these side effects are often under-reported and you can begin to see how even a single pharmaceutical, let alone a cocktail of them can damage the body over time. If you need to take pharmaceuticals, then consider using glutathione to remove their often toxic metabolic end products from your body.
Toxic Metals
While glutathione (when assisted by glutathione-s-transferase) removes toxic metals like mercury, lead and aluminum from the body, it is far more valuable in its ability to remove toxic chemicals.
Among glutathione’s many important properties are:
Detoxification/Chelation
Heavy metal toxicity including mercury, lead, arsenic and cadmium
Common toxins that glutathione may help protect against are car exhaust, cigarette smoke, aspirin and alcohol
Pesticide and industrial chemical exposure
Steroids
Bacterial toxins
Pharmaceuticals
Immune enhancement: 1-3 g per day. This is especially effective against clostridium in the GI. It helps prevent translocation.
Psoriasis
Diabetes mellitus: Especially in ketosis as DM patients will generally excrete increased amounts of sulfur containing amino acids.
Liver disease including cirrhosis and fatty liver disease caused by alcohol: Clinical Research and Case studies show significant improvement in as little as 2 weeks.
Ulcers intestinal or stomach: In patients with stomach ulcers low levels of GSH have been found.
Aspirin or phenacetin overdose (useful for rheumatoid arthritis patients or chronic pain sufferers on 8 or more aspirin/day)
Disclaimer: The statements above have not been evaluated by the FDA. The nutritional suggestions and research provided are for informational purposes only and are not intended to diagnose, treat, cure or prevent disease and should not be used as a substitute for sound medical advice. Please see your health care professional in all matters pertaining to your physical health.
